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Transrepressive Function of TLX Requires the Histone Demethylase LSD1

TLX is an orphan nuclear receptor (also called NR2E1) that regulates the expression of target genes by functioning as a constitutive transrepressor. The physiological significance of TLX in the cytodifferentiation of neural cells in the brain is known. However, the corepressors supporting the transr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yokoyama, Atsushi, Takezawa, Shinichiro, Schüle, Roland, Kitagawa, Hirochika, Kato, Shigeaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423124/
https://ncbi.nlm.nih.gov/pubmed/18391013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02030-07
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