Nanoscale Assembly of High-Mobility Group AT-Hook 2 Protein with DNA Replication Fork

High mobility group AT-hook 2 (HMGA2) protein is composed of three AT-hook domains. HMGA2 expresses at high levels in both embryonic stem cells and cancer cells, where it interacts with and stabilizes replication forks (RFs), resulting in elevated cell proliferation rates. In this study, we demonstr...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Krahn, Natalie, Meier, Markus, To, Vu, Booy, Evan P., McEleney, Kevin, O’Neil, Joe D., McKenna, Sean A., Patel, Trushar R., Stetefeld, Jörg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2017
Onderwerpen:
Nucleic Acids and Genome Biophysics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771026/
https://ncbi.nlm.nih.gov/pubmed/29262356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.026
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