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Structural and Hydrodynamic Characterization of Dimeric Human Oligoadenylate Synthetase 2
Oligoadenylate synthetases (OASs) are a family of interferon-inducible enzymes that require double-stranded RNA (dsRNA) as a cofactor. Upon binding dsRNA, OAS undergoes a conformational change and is activated to polymerize ATP into 2′-5′-oligoadenylate chains. The OAS family consists of several iso...
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| Vydáno v: | Biophys J |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Biophysical Society
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7264852/ https://ncbi.nlm.nih.gov/pubmed/32413313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.025 |
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