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Activation of 2′ 5′-Oligoadenylate Synthetase by Stem Loops at the 5′-End of the West Nile Virus Genome

West Nile virus (WNV) has a positive sense RNA genome with conserved structural elements in the 5′ and 3′ -untranslated regions required for polyprotein production. Antiviral immunity to WNV is partially mediated through the production of a cluster of proteins known as the interferon stimulated gene...

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Hlavní autoři: Deo, Soumya, Patel, Trushar R., Dzananovic, Edis, Booy, Evan P., Zeid, Khalid, McEleney, Kevin, Harding, Stephen E., McKenna, Sean A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961380/
https://ncbi.nlm.nih.gov/pubmed/24651762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092545
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