Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU

Nucleic acids rich in guanine are able to fold into unique structures known as G-quadruplexes. G-quadruplexes consist of four tracts of guanylates arranged in parallel or antiparallel strands that are aligned in stacked G-quartet planes. The structure is further stabilized by Hoogsteen hydrogen bond...

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Publicat a:PLoS One
Autors principals: Ariyo, Emmanuel O., Booy, Evan P., Patel, Trushar R., Dzananovic, Edis, McRae, Ewan K., Meier, Markus, McEleney, Kevin, Stetefeld, Jorg, McKenna, Sean A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674103/
https://ncbi.nlm.nih.gov/pubmed/26649896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144510
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