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Polygenic hazard scores in preclinical Alzheimer’s disease
Identifying asymptomatic older individuals at elevated risk for developing Alzheimer’s disease (AD) is of clinical importance. Among 1,081 asymptomatic older adults, a recently validated polygenic hazard score (PHS) significantly predicted time to AD dementia and steeper longitudinal cognitive decli...
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| Udgivet i: | Ann Neurol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758043/ https://ncbi.nlm.nih.gov/pubmed/28940650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25029 |
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