Polygenic hazard scores in preclinical Alzheimer’s disease

Identifying asymptomatic older individuals at elevated risk for developing Alzheimer’s disease (AD) is of clinical importance. Among 1,081 asymptomatic older adults, a recently validated polygenic hazard score (PHS) significantly predicted time to AD dementia and steeper longitudinal cognitive decli...

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Detaylı Bibliyografya
Yayımlandı:Ann Neurol
Asıl Yazarlar: Tan, Chin Hong, Hyman, Bradley T., Tan, Jacinth J. X., Hess, Christopher P., Dillon, William P., Schellenberg, Gerard D., Besser, Lilah M., Kukull, Walter A., Kauppi, Karolina, McEvoy, Linda K., Andreassen, Ole A., Dale, Anders M., Fan, Chun Chieh, Desikan, Rahul S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758043/
https://ncbi.nlm.nih.gov/pubmed/28940650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25029
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