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Polygenic hazard scores in preclinical Alzheimer’s disease

Identifying asymptomatic older individuals at elevated risk for developing Alzheimer’s disease (AD) is of clinical importance. Among 1,081 asymptomatic older adults, a recently validated polygenic hazard score (PHS) significantly predicted time to AD dementia and steeper longitudinal cognitive decli...

詳細記述

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書誌詳細
出版年:Ann Neurol
主要な著者: Tan, Chin Hong, Hyman, Bradley T., Tan, Jacinth J. X., Hess, Christopher P., Dillon, William P., Schellenberg, Gerard D., Besser, Lilah M., Kukull, Walter A., Kauppi, Karolina, McEvoy, Linda K., Andreassen, Ole A., Dale, Anders M., Fan, Chun Chieh, Desikan, Rahul S.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758043/
https://ncbi.nlm.nih.gov/pubmed/28940650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25029
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