HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity

The maintenance and functional integrity of long-term hematopoietic stem cells (LT-HSCs) is critical for lifelong hematopoietic regeneration. Histone deacetylases (HDACs) modulate acetylation of lysine residues, a protein modification important for regulation of numerous biological processes. Here,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Hua, Wei-Kai, Qi, Jing, Cai, Qi, Carnahan, Emily, Ayala Ramirez, Maria, Li, Ling, Marcucci, Guido, Kuo, Ya-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731083/
https://ncbi.nlm.nih.gov/pubmed/29084772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-03-771386
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados