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Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates
Hematopoietic stem cells (HSCs) undergo self-renewal or differentiation to sustain lifelong hematopoiesis. HSCs are preserved in quiescence with low mitochondrial activity. Recent studies indicate that autophagy contributes to HSC quiescence through suppressing mitochondrial metabolism. However, it...
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| Veröffentlicht in: | Blood Adv |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7993101/ https://ncbi.nlm.nih.gov/pubmed/33710340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002410 |
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