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Regain control of p53: targeting leukemia stem cells by isoform-specific HDAC inhibition
Leukemia stem cells (LSCs) are self-renewable leukemia-initiating populations that are often resistant to traditional chemotherapy and tyrosine kinase inhibitors (TKI) currently used for treatment of acute or chronic myeloid leukemia (AML or CML). The persistence and continued acquisition of mutatio...
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| Publicado no: | Exp Hematol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4841712/ https://ncbi.nlm.nih.gov/pubmed/26923266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.02.007 |
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