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HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity
The maintenance and functional integrity of long-term hematopoietic stem cells (LT-HSCs) is critical for lifelong hematopoietic regeneration. Histone deacetylases (HDACs) modulate acetylation of lysine residues, a protein modification important for regulation of numerous biological processes. Here,...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5731083/ https://ncbi.nlm.nih.gov/pubmed/29084772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-03-771386 |
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