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Pushing the Limits: Defeating Leukemia Stem Cells by Depleting Telomerase
Leukemia stem cells (LSCs), featuring unlimited self-renewal capacity and chemoresistance, are critical cellular targets for new treatments to improve outcomes for acute myeloid leukemia (AML). In this issue, Bruedigam et al. demonstrate that inhibition of telomerase is damaging to LSCs and may repr...
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| Vydáno v: | Cell Stem Cell |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394378/ https://ncbi.nlm.nih.gov/pubmed/25479742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.11.014 |
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