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Pushing the Limits: Defeating Leukemia Stem Cells by Depleting Telomerase
Leukemia stem cells (LSCs), featuring unlimited self-renewal capacity and chemoresistance, are critical cellular targets for new treatments to improve outcomes for acute myeloid leukemia (AML). In this issue, Bruedigam et al. demonstrate that inhibition of telomerase is damaging to LSCs and may repr...
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| Publicado no: | Cell Stem Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394378/ https://ncbi.nlm.nih.gov/pubmed/25479742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.11.014 |
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