Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions

Besides being a classical tumor suppressor, runt-related transcription factor 1 (RUNX1) is now widely recognized for its oncogenic role in the development of acute myeloid leukemia (AML). Here we report that this bidirectional function of RUNX1 possibly arises from the total level of RUNX family exp...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Morita, Ken, Maeda, Shintaro, Suzuki, Kensho, Kiyose, Hiroki, Taniguchi, Junichi, Liu, Pu Paul, Sugiyama, Hiroshi, Adachi, Souichi, Kamikubo, Yasuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727854/
https://ncbi.nlm.nih.gov/pubmed/29296785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007591
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