Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions

Besides being a classical tumor suppressor, runt-related transcription factor 1 (RUNX1) is now widely recognized for its oncogenic role in the development of acute myeloid leukemia (AML). Here we report that this bidirectional function of RUNX1 possibly arises from the total level of RUNX family exp...

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Morita, Ken, Maeda, Shintaro, Suzuki, Kensho, Kiyose, Hiroki, Taniguchi, Junichi, Liu, Pu Paul, Sugiyama, Hiroshi, Adachi, Souichi, Kamikubo, Yasuhiko
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2017
Teme:
Myeloid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727854/
https://ncbi.nlm.nih.gov/pubmed/29296785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007591
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