Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions

Besides being a classical tumor suppressor, runt-related transcription factor 1 (RUNX1) is now widely recognized for its oncogenic role in the development of acute myeloid leukemia (AML). Here we report that this bidirectional function of RUNX1 possibly arises from the total level of RUNX family exp...

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Publicado en:Blood Adv
Autores principales: Morita, Ken, Maeda, Shintaro, Suzuki, Kensho, Kiyose, Hiroki, Taniguchi, Junichi, Liu, Pu Paul, Sugiyama, Hiroshi, Adachi, Souichi, Kamikubo, Yasuhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2017
Materias:
Myeloid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727854/
https://ncbi.nlm.nih.gov/pubmed/29296785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007591
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