Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions

Besides being a classical tumor suppressor, runt-related transcription factor 1 (RUNX1) is now widely recognized for its oncogenic role in the development of acute myeloid leukemia (AML). Here we report that this bidirectional function of RUNX1 possibly arises from the total level of RUNX family exp...

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Vydáno v:Blood Adv
Hlavní autoři: Morita, Ken, Maeda, Shintaro, Suzuki, Kensho, Kiyose, Hiroki, Taniguchi, Junichi, Liu, Pu Paul, Sugiyama, Hiroshi, Adachi, Souichi, Kamikubo, Yasuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2017
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727854/
https://ncbi.nlm.nih.gov/pubmed/29296785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007591
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