Genetic regulation of the RUNX transcription factor family has antitumor effects

Runt-related transcription factor 1 (RUNX1) is generally considered to function as a tumor suppressor in the development of leukemia, but a growing body of evidence suggests that it has pro-oncogenic properties in acute myeloid leukemia (AML). Here we have demonstrated that the antileukemic effect m...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Morita, Ken, Suzuki, Kensho, Maeda, Shintaro, Matsuo, Akihiko, Mitsuda, Yoshihide, Tokushige, Chieko, Kashiwazaki, Gengo, Taniguchi, Junichi, Maeda, Rina, Noura, Mina, Hirata, Masahiro, Kataoka, Tatsuki, Yano, Ayaka, Yamada, Yoshimi, Kiyose, Hiroki, Tokumasu, Mayu, Matsuo, Hidemasa, Tanaka, Sunao, Okuno, Yasushi, Muto, Manabu, Naka, Kazuhito, Ito, Kosei, Kitamura, Toshio, Kaneda, Yasufumi, Liu, Paul P., Bando, Toshikazu, Adachi, Souichi, Sugiyama, Hiroshi, Kamikubo, Yasuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490777/
https://ncbi.nlm.nih.gov/pubmed/28530640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91788
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