KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

KIT mutations are the most common secondary mutations in inv(16) acute myeloid leukemia (AML) patients and are associated with poor prognosis. It is therefore important to verify that KIT mutations cooperate with CBFB-MYH11, the fusion gene generated by inv(16), for leukemogenesis. Here, we transduc...

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Bibliographic Details
Main Authors:	Zhao, Ling, Melenhorst, Jan J., Alemu, Lemlem, Kirby, Martha, Anderson, Stacie, Kench, Maggie, Hoogstraten-Miller, Shelley, Brinster, Lauren, Kamikubo, Yasuhiko, Gilliland, D. Gary, Liu, P. Paul
Format:	Artigo
Language:	Inglês
Published:	American Society of Hematology 2012
Subjects:	Myeloid Neoplasia
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3286214/ https://ncbi.nlm.nih.gov/pubmed/22160378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-338210
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KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

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