KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

KIT mutations are the most common secondary mutations in inv(16) acute myeloid leukemia (AML) patients and are associated with poor prognosis. It is therefore important to verify that KIT mutations cooperate with CBFB-MYH11, the fusion gene generated by inv(16), for leukemogenesis. Here, we transduc...

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Detalhes bibliográficos
Main Authors: Zhao, Ling, Melenhorst, Jan J., Alemu, Lemlem, Kirby, Martha, Anderson, Stacie, Kench, Maggie, Hoogstraten-Miller, Shelley, Brinster, Lauren, Kamikubo, Yasuhiko, Gilliland, D. Gary, Liu, P. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286214/
https://ncbi.nlm.nih.gov/pubmed/22160378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-338210
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