RNAi mechanisms in Huntington’s disease therapy: siRNA versus shRNA

Huntington’s Disease (HD) is a genetically dominant trinucleotide repeat disorder resulting from CAG repeats within the Huntingtin (HTT) gene exceeding a normal range (> 36 CAGs). Symptoms of the disease manifest in middle age and include chorea, dystonia, and cognitive decline. Typical latency f...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Transl Neurodegener
Main Authors: Aguiar, Sebastian, van der Gaag, Bram, Cortese, Francesco Albert Bosco
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702971/
https://ncbi.nlm.nih.gov/pubmed/29209494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0101-9
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker