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Current Progress of siRNA/shRNA Therapeutics in Clinical Trials
Through a mechanism known as RNA interference (RNAi), small interfering RNA (siRNA) molecules can target complementary mRNA strands for degradation, thus specifically inhibiting gene expression. The ability of siRNAs to inhibit gene expression offers a mechanism that can be exploited for novel thera...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388104/ https://ncbi.nlm.nih.gov/pubmed/21744502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201100054 |
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