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Current Progress of siRNA/shRNA Therapeutics in Clinical Trials

Through a mechanism known as RNA interference (RNAi), small interfering RNA (siRNA) molecules can target complementary mRNA strands for degradation, thus specifically inhibiting gene expression. The ability of siRNAs to inhibit gene expression offers a mechanism that can be exploited for novel thera...

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Hlavní autoři: Burnett, John C., Rossi, John J., Tiemann, Katrin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388104/
https://ncbi.nlm.nih.gov/pubmed/21744502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201100054
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