Structure–Activity Relationships of [des-Arg(7)]Dynorphin A Analogues at the κ Opioid Receptor

Dynorphin A (Dyn A) is an endogenous ligand for the opioid receptors with preference for the κ opioid receptor (KOR), and its structure–activity relationship (SAR) has been extensively studied at the KOR to develop selective potent agonists and antagonists. Numerous SAR studies have revealed that th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Med Chem
Prif Awduron: Ramos-Colon, Cyf N., Lee, Yeon Sun, Remesic, Michael, Hall, Sara M., LaVigne, Justin, Davis, Peg, Sandweiss, Alexander J., McIntosh, Mary I., Hanson, Jessica, Largent-Milnes, Tally M., Vanderah, Todd W., Streicher, John, Porreca, Frank, Hruby, Victor J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693303/
https://ncbi.nlm.nih.gov/pubmed/27797517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01411
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