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Structure-activity relationships of non-opioid [des-Arg(7)]-dynorphin A analogues for bradykinin receptors
In our earlier studies, bradykinin receptors (BRs) were identified as a potential target for the neuroexcitatory effects of dynorphin A (Dyn A) in the central nervous system (CNS), and [des-Arg(7)]-Dyn A-(4-11) (6) was discovered as a lead ligand to modulate Dyn A-(2-13) induced neuroexcitatory effe...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250343/ https://ncbi.nlm.nih.gov/pubmed/25282551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.09.033 |
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