Structure–Activity Relationships of [des-Arg(7)]Dynorphin A Analogues at the κ Opioid Receptor

Dynorphin A (Dyn A) is an endogenous ligand for the opioid receptors with preference for the κ opioid receptor (KOR), and its structure–activity relationship (SAR) has been extensively studied at the KOR to develop selective potent agonists and antagonists. Numerous SAR studies have revealed that th...

詳細記述

保存先:
書誌詳細
出版年:J Med Chem
主要な著者: Ramos-Colon, Cyf N., Lee, Yeon Sun, Remesic, Michael, Hall, Sara M., LaVigne, Justin, Davis, Peg, Sandweiss, Alexander J., McIntosh, Mary I., Hanson, Jessica, Largent-Milnes, Tally M., Vanderah, Todd W., Streicher, John, Porreca, Frank, Hruby, Victor J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693303/
https://ncbi.nlm.nih.gov/pubmed/27797517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01411
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