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Suppressing allostery in epitope mapping experiments using millisecond hydrogen / deuterium exchange mass spectrometry
Localization of the interface between the candidate antibody and its antigen target, commonly known as epitope mapping, is a critical component of the development of therapeutic monoclonal antibodies. With the recent availability of commercial automated systems, hydrogen / deuterium eXchange (HDX) i...
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| 發表在: | MAbs |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680795/ https://ncbi.nlm.nih.gov/pubmed/28933661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1379641 |
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