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Hydrogen–deuterium exchange reveals long-range dynamical allostery in soybean lipoxygenase

In lipoxygenases, the topologically conserved C-terminal domain catalyzes the oxidation of polyunsaturated fatty acids, generating an assortment of biologically relevant signaling mediators. Plant and animal lipoxygenases also contain a 100-150-amino acid N-terminal C2-like domain that has been impl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Offenbacher, Adam R., Iavarone, Anthony T., Klinman, Judith P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787793/
https://ncbi.nlm.nih.gov/pubmed/29191828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.817197
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