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Hydrogen-Deuterium Exchange Mass Spectrometry Reveals Folding and Allostery in Protein-Protein Interactions

Hydrogen-deuterium exchange mass spectrometry (HDXMS) has emerged as a powerful approach for revealing folding and allostery in protein-protein interactions. The advent of higher resolution mass spectrometers combined with ion mobility separation and ultra-high liquid chromatographic separations hav...

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Bibliographic Details
Published in:Methods
Main Authors: Ramirez-Sarmiento, Cesar A., Komives, Elizabeth A.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051914/
https://ncbi.nlm.nih.gov/pubmed/29627358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.04.001
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