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Hydrogen–Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling
[Image: see text] Defining specific pathways for efficient heat transfer from protein–solvent interfaces to their active sites represents one of the compelling and timely challenges in our quest for a physical description of the origins of enzyme catalysis. Enzymatic hydrogen tunneling reactions con...
שמור ב:
| הוצא לאור ב: | ACS Cent Sci |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical Society
2017
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5492416/ https://ncbi.nlm.nih.gov/pubmed/28691068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00142 |
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