GUCY2C signaling opposes the acute radiation-induced GI syndrome

High doses of ionizing radiation induce acute damage to epithelial cells of the gastrointestinal (GI) tract, mediating toxicities restricting the therapeutic efficacy of radiation in cancer and morbidity and mortality in nuclear disasters. No approved prophylaxis or therapy exists for these toxiciti...

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Bibliografiske detaljer
Udgivet i:	Cancer Res
Main Authors:	Li, Peng, Wuthrick, Evan, Rappaport, Jeff A., Kraft, Crystal, Lin, Jieru E., Marszalowicz, Glen, Snook, Adam E., Zhan, Tingting, Hyslop, Terry M., Waldman, Scott A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2017
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5678756/ https://ncbi.nlm.nih.gov/pubmed/28916678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0859
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GUCY2C signaling opposes the acute radiation-induced GI syndrome

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