GUCY2C maintains intestinal LGR5(+) stem cells by opposing ER stress

Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential underlie the necessity for tight homeostatic regulation...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Kraft, Crystal L., Rappaport, Jeffrey A., Snook, Adam E., Pattison, Amanda M., Lynch, John P., Waldman, Scott A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732700/
https://ncbi.nlm.nih.gov/pubmed/29262534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22084
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