GUCY2C maintains intestinal LGR5(+) stem cells by opposing ER stress

Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential underlie the necessity for tight homeostatic regulation...

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發表在:Oncotarget
Main Authors: Kraft, Crystal L., Rappaport, Jeffrey A., Snook, Adam E., Pattison, Amanda M., Lynch, John P., Waldman, Scott A.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732700/
https://ncbi.nlm.nih.gov/pubmed/29262534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22084
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