GUCY2C signaling opposes the acute radiation-induced GI syndrome

High doses of ionizing radiation induce acute damage to epithelial cells of the gastrointestinal (GI) tract, mediating toxicities restricting the therapeutic efficacy of radiation in cancer and morbidity and mortality in nuclear disasters. No approved prophylaxis or therapy exists for these toxiciti...

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Pubblicato in:Cancer Res
Autori principali: Li, Peng, Wuthrick, Evan, Rappaport, Jeff A., Kraft, Crystal, Lin, Jieru E., Marszalowicz, Glen, Snook, Adam E., Zhan, Tingting, Hyslop, Terry M., Waldman, Scott A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678756/
https://ncbi.nlm.nih.gov/pubmed/28916678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0859
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