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Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C

Guanylyl cyclase C (GUCY2C) is the index cancer mucosa antigen, an emerging class of immunotherapeutic targets for the prevention of recurrent metastases originating in visceral epithelia. GUCY2C is an autoantigen principally expressed by intestinal epithelium, and universally by primary and metasta...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Snook, Adam E., Magee, Michael S., Marszalowicz, Glen P., Schulz, Stephanie, Waldman, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880860/
https://ncbi.nlm.nih.gov/pubmed/22057677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1133-0
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