A uroguanylin-GUCY2C endocrine axis regulates feeding in mice

Intestinal enteroendocrine cells are critical to central regulation of caloric consumption, since they activate hypothalamic circuits that decrease appetite and thereby restrict meal size by secreting hormones in response to nutrients in the gut. Although guanylyl cyclase and downstream cGMP are ess...

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Bibliografiske detaljer
Main Authors: Valentino, Michael A., Lin, Jieru E., Snook, Adam E., Li, Peng, Kim, Gilbert W., Marszalowicz, Glen, Magee, Michael S., Hyslop, Terry, Schulz, Stephanie, Waldman, Scott A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223926/
https://ncbi.nlm.nih.gov/pubmed/21865642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57925
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