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Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C

Guanylyl cyclase C (GUCY2C) is the index cancer mucosa antigen, an emerging class of immunotherapeutic targets for the prevention of recurrent metastases originating in visceral epithelia. GUCY2C is an autoantigen principally expressed by intestinal epithelium, and universally by primary and metasta...

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書目詳細資料
發表在:Cancer Immunol Immunother
Main Authors: Snook, Adam E., Magee, Michael S., Marszalowicz, Glen P., Schulz, Stephanie, Waldman, Scott A.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880860/
https://ncbi.nlm.nih.gov/pubmed/22057677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1133-0
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