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Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C

Guanylyl cyclase C (GUCY2C) is the index cancer mucosa antigen, an emerging class of immunotherapeutic targets for the prevention of recurrent metastases originating in visceral epithelia. GUCY2C is an autoantigen principally expressed by intestinal epithelium, and universally by primary and metasta...

詳細記述

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書誌詳細
出版年:Cancer Immunol Immunother
主要な著者: Snook, Adam E., Magee, Michael S., Marszalowicz, Glen P., Schulz, Stephanie, Waldman, Scott A.
フォーマット: Artigo
言語:Inglês
出版事項: Springer-Verlag 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880860/
https://ncbi.nlm.nih.gov/pubmed/22057677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1133-0
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