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Loss of p300 Accelerates MDS-associated Leukemogenesis

The role that changes in DNA methylation and histone modifications play in human malignancies is poorly understood. p300 and CBP, two distinct but highly homologous lysine acetyltransferases (KATs), are mutated in several cancers, suggesting their role as tumor suppressors. In the current study, we...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Leukemia
Main Authors: Cheng, Guoyan, Liu, Fan, Asai, Takashi, Lai, Fan, Man, Na, Xu, Haiming, Chen, Shi, Greenblatt, Sarah, Hamard, Pierre-Jacques, Ando, Koji, Martinez, Conception, Tadi, Madhavi, Wang, Lan, Xu, Mingjiang, Yang, Feng-Chun, Shiekhattar, Ramin, Nimer, Stephen D.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667352/
https://ncbi.nlm.nih.gov/pubmed/27881875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.347
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