Loss of p300 Accelerates MDS-associated Leukemogenesis

The role that changes in DNA methylation and histone modifications play in human malignancies is poorly understood. p300 and CBP, two distinct but highly homologous lysine acetyltransferases (KATs), are mutated in several cancers, suggesting their role as tumor suppressors. In the current study, we...

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發表在:Leukemia
Main Authors: Cheng, Guoyan, Liu, Fan, Asai, Takashi, Lai, Fan, Man, Na, Xu, Haiming, Chen, Shi, Greenblatt, Sarah, Hamard, Pierre-Jacques, Ando, Koji, Martinez, Conception, Tadi, Madhavi, Wang, Lan, Xu, Mingjiang, Yang, Feng-Chun, Shiekhattar, Ramin, Nimer, Stephen D.
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667352/
https://ncbi.nlm.nih.gov/pubmed/27881875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.347
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