CARM1 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis

Chromatin modifying enzymes, and specifically the protein arginine methyltransferases (PRMTs) have emerged as important targets in cancer. Here, we investigated the role of CARM1 in normal and malignant hematopoiesis. Using conditional knockout mice, we show that loss of CARM1 has little effect on n...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cancer Cell
Главные авторы: Greenblatt, Sarah M., Man, Na, Hamard, Pierre-Jacques, Asai, Takashi, Karl, Daniel, Martinez, Concepcion, Bilbao, Daniel, Stathais, Vasileios, McGrew-Jermacowicz, Anna, Duffort, Stephanie, Tadi, Madhavi, Blumenthal, Ezra, Newman, Samantha, Vu, Ly, Xu, Ye, Liu, Fan, Schurer, Stephan C., McCabe, Michael T., Kruger, Ryan G., Xu, Mingjiang, Yang, Feng-Chun, Tenen, Daniel, Watts, Justin, Vega, Francisco, Nimer, Stephen D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191185/
https://ncbi.nlm.nih.gov/pubmed/29894694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.05.007
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы