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PTEN in Regulating Hematopoiesis and Leukemogenesis
PTEN is one of the most frequently mutated tumor suppressor genes in human cancers. By counteracting the PI3K/AKT/mTOR pathway, PTEN plays an essential role in regulating hematopoietic stem cells (HSCs) self-renewal, migration, lineage commitment, and differentiation. PTEN also plays important roles...
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| Publicado no: | Cold Spring Harb Perspect Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7528863/ https://ncbi.nlm.nih.gov/pubmed/31712222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036244 |
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