Direct, enantioselective α-alkylation of aldehydes using simple olefins

Although the α-alkylation of ketones has already been established, the analogous reaction using aldehyde substrates has proven surprisingly elusive. Despite the structural similarities between the two classes of compounds, the sensitivity and unique reactivity of the aldehyde functionality has typic...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem
Asıl Yazarlar: Capacci, Andrew G., Malinowski, Justin T., McAlpine, Neil J., Kuhne, Jerome, MacMillan, David W. C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665178/
https://ncbi.nlm.nih.gov/pubmed/29064486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2797
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