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Direct, enantioselective α-alkylation of aldehydes using simple olefins
Although the α-alkylation of ketones has already been established, the analogous reaction using aldehyde substrates has proven surprisingly elusive. Despite the structural similarities between the two classes of compounds, the sensitivity and unique reactivity of the aldehyde functionality has typic...
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| Pubblicato in: | Nat Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5665178/ https://ncbi.nlm.nih.gov/pubmed/29064486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2797 |
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