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Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues
Current drugs to treat African sleeping sickness are inadequate and new therapies are urgently required. As part of a medicinal chemistry programme based upon the simplification of acetogenin-type ether scaffolds, we previously reported the promising trypanocidal activity of compound 1, a bis-tetrah...
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| Publicado no: | PLoS Negl Trop Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608556/ https://ncbi.nlm.nih.gov/pubmed/28873407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005886 |
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