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Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues
Current drugs to treat African sleeping sickness are inadequate and new therapies are urgently required. As part of a medicinal chemistry programme based upon the simplification of acetogenin-type ether scaffolds, we previously reported the promising trypanocidal activity of compound 1, a bis-tetrah...
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| 出版年: | PLoS Negl Trop Dis |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608556/ https://ncbi.nlm.nih.gov/pubmed/28873407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005886 |
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