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Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors

Neglected tropical diseases caused by parasitic infections are an ongoing and increasing concern. They are a burden to human and animal health, having the most devastating effect on the world′s poorest countries. Building upon our previously reported triazole analogues, in this study we describe the...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Florence, Gordon J., Fraser, Andrew L., Gould, Eoin R., King, Elizabeth F., Menzies, Stefanie K., Morris, Joanne C., Thomson, Marie I., Tulloch, Lindsay B., Zacharova, Marija K., Smith, Terry K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111590/
https://ncbi.nlm.nih.gov/pubmed/27283448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600210
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