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PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)
Endoplasmic reticulum (ER) stress leads to activation of the unfolded protein response (UPR) that results in transient suppression of protein translation to allow recovery but leads to cell death when stress cannot be resolved. Central to initiation of the UPR is the activation of the ER transmembra...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5596557/ https://ncbi.nlm.nih.gov/pubmed/28796255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.369 |
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