Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing

For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues. Herein, we show that Streptococcus pneumoniae that invade the myocardium instead replicate within cellular vesicles an...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Shenoy, Anukul T., Brissac, Terry, Gilley, Ryan P., Kumar, Nikhil, Wang, Yong, Gonzalez-Juarbe, Norberto, Hinkle, Whitney S., Daugherty, Sean C., Shetty, Amol C., Ott, Sandra, Tallon, Luke J., Deshane, Jessy, Tettelin, Hervé, Orihuela, Carlos J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589263/
https://ncbi.nlm.nih.gov/pubmed/28841717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006582
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