Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing

For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues. Herein, we show that Streptococcus pneumoniae that invade the myocardium instead replicate within cellular vesicles an...

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Pubblicato in:PLoS Pathog
Autori principali: Shenoy, Anukul T., Brissac, Terry, Gilley, Ryan P., Kumar, Nikhil, Wang, Yong, Gonzalez-Juarbe, Norberto, Hinkle, Whitney S., Daugherty, Sean C., Shetty, Amol C., Ott, Sandra, Tallon, Luke J., Deshane, Jessy, Tettelin, Hervé, Orihuela, Carlos J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589263/
https://ncbi.nlm.nih.gov/pubmed/28841717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006582
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