Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion

Streptococcus pneumoniae (the pneumococcus) is capable of invading the heart. Herein we observed that pneumococcal invasion of the myocardium occurred soon after development of bacteremia and was continuous thereafter. Using immunofluorescence microscopy (IFM), we observed that S. pneumoniae replica...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Gilley, Ryan P., González-Juarbe, Norberto, Shenoy, Anukul T., Reyes, Luis F., Dube, Peter H., Restrepo, Marcos I., Orihuela, Carlos J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862731/
https://ncbi.nlm.nih.gov/pubmed/26930705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00007-16
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