Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion

Streptococcus pneumoniae (the pneumococcus) is capable of invading the heart. Herein we observed that pneumococcal invasion of the myocardium occurred soon after development of bacteremia and was continuous thereafter. Using immunofluorescence microscopy (IFM), we observed that S. pneumoniae replica...

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Vydáno v:Infect Immun
Hlavní autoři: Gilley, Ryan P., González-Juarbe, Norberto, Shenoy, Anukul T., Reyes, Luis F., Dube, Peter H., Restrepo, Marcos I., Orihuela, Carlos J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Bacterial Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862731/
https://ncbi.nlm.nih.gov/pubmed/26930705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00007-16
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