Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion

Streptococcus pneumoniae (the pneumococcus) is capable of invading the heart. Herein we observed that pneumococcal invasion of the myocardium occurred soon after development of bacteremia and was continuous thereafter. Using immunofluorescence microscopy (IFM), we observed that S. pneumoniae replica...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Gilley, Ryan P., González-Juarbe, Norberto, Shenoy, Anukul T., Reyes, Luis F., Dube, Peter H., Restrepo, Marcos I., Orihuela, Carlos J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Bacterial Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862731/
https://ncbi.nlm.nih.gov/pubmed/26930705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00007-16
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