Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion

Streptococcus pneumoniae (the pneumococcus) is capable of invading the heart. Herein we observed that pneumococcal invasion of the myocardium occurred soon after development of bacteremia and was continuous thereafter. Using immunofluorescence microscopy (IFM), we observed that S. pneumoniae replica...

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Publicat a:Infect Immun
Autors principals: Gilley, Ryan P., González-Juarbe, Norberto, Shenoy, Anukul T., Reyes, Luis F., Dube, Peter H., Restrepo, Marcos I., Orihuela, Carlos J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Bacterial Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862731/
https://ncbi.nlm.nih.gov/pubmed/26930705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00007-16
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