Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia

We report that pore-forming toxins (PFTs) induce respiratory epithelial cell necroptosis independently of death receptor signaling during bacterial pneumonia. Instead, necroptosis was activated as a result of ion dysregulation arising from membrane permeabilization. PFT-induced necroptosis required...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: González-Juarbe, Norberto, Bradley, Kelley Margaret, Shenoy, Anukul Taranath, Gilley, Ryan Paul, Reyes, Luis Felipe, Hinojosa, Cecilia Anahí, Restrepo, Marcos Ignacio, Dube, Peter Herman, Bergman, Molly Ann, Orihuela, Carlos Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423117/
https://ncbi.nlm.nih.gov/pubmed/28387756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.49
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados