Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing

For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues. Herein, we show that Streptococcus pneumoniae that invade the myocardium instead replicate within cellular vesicles an...

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Udgivet i:PLoS Pathog
Main Authors: Shenoy, Anukul T., Brissac, Terry, Gilley, Ryan P., Kumar, Nikhil, Wang, Yong, Gonzalez-Juarbe, Norberto, Hinkle, Whitney S., Daugherty, Sean C., Shetty, Amol C., Ott, Sandra, Tallon, Luke J., Deshane, Jessy, Tettelin, Hervé, Orihuela, Carlos J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589263/
https://ncbi.nlm.nih.gov/pubmed/28841717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006582
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